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1.
Chinese Journal of Integrated Traditional and Western Medicine ; (12): 882-884, 2004.
Article in Chinese | WPRIM | ID: wpr-306759

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the effect of compound Salvia injection (CSI) on blood coagulatory function in patients with traumatic cerebral infarction (TCI).</p><p><b>METHODS</b>Sixty-four patients with TCI were randomly divided into two groups, 32 in each group. The treated group were treated with CSI plus conventional treatment of western medicine, and the control group treated with conventional treatment alone. Changes of symptoms, levels of plasma P-selectin (P-S), von Willebrand's factor (vWf) and D-dimer were observed with ELISA.</p><p><b>RESULTS</b>The treated group was superior to the control group in Glasgow outcome scale (P < 0.01). Before treatment, the levels of plasma P-S, vWf and D-dimer in the TCI patients were higher than those in healthy people. After treatment, all the parameters lowered in both groups, but the effect of lowering was greater in the treated group than that in the control group.</p><p><b>CONCLUSION</b>Blood coagulation disorder exists in patients with TCI, CSI could improve it, and might alleviate the cerebral damage to a certain extent.</p>


Subject(s)
Female , Humans , Male , Blood Coagulation , Brain Injuries , Cerebral Infarction , Drug Therapy , Drugs, Chinese Herbal , Therapeutic Uses , Free Radical Scavengers , Therapeutic Uses , Injections, Intravenous , P-Selectin , Blood , Phytotherapy , Salvia miltiorrhiza , Chemistry , Superoxide Dismutase , Blood , von Willebrand Factor , Metabolism
2.
Chinese Traditional and Herbal Drugs ; (24)1994.
Article in Chinese | WPRIM | ID: wpr-681157

ABSTRACT

Object To carry out a deeper study on the active component and the structure of Aloe vera L. var chinensis (Haw ) Berg Methods The polysaccharide was isolated from the extract of the fresh leaf pulp of A. vera var chinensis by means of DEAE Sephadex A 25 ion exchange column chromatography and identified, through HPLC, IR, TGA, 13 CNMR and elementary analysis Results Alkaline hydrolysis proved that it is a neutral, linear polymer of a partially acetylated ? 1, 4 D mannopyranose of high purity The molar ratio of D mannose to the acetyl group in the polysaccharide was 1 64∶1 Conclusion This is the first report to uncover the presence of such polysaccharide in A vera var chinensis

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